FEF Frontal Eye Field

Stream: dorsal where safe
Classical equivalent: Caudal Middle Frontal Gyrus, LH: i6-8, R: 6a (Bedini (2023) - Brain Structure), BA6 + BA8 (Bedini & Baldauf (2021))
Mapped to Glasser: FEF

this region’s structure, function and connectivity in humans are often debated and are not yet fully understood. (Bedini & Baldauf (2021))

MNI Coordinates

Right: [30 −6 50] (Bedini (2023) - Brain Structure), [35.71±10.77 -2.96±4.85 53.19±5.55] (Bedini & Baldauf (2021))
Left: [−28 −6 54] (Bedini (2023) - Brain Structure), [-34.6±12.31 -5.42±6.28 50.24±6.99] (Bedini & Baldauf (2021))

The frontal eye field (FEF) is located in area 8.
The FEF is localized ventral to the junction of the sPCS and the SFS (Bedini & Baldauf (2021))
BA6 + BA8 (Bedini & Baldauf (2021))
FEF contains a mal of saccade targets, i.e. is topographically organised, and its stimulation triggers saccades. (n.n)
- FEF contains a full topographic map of contralateral space. (Bedini & Baldauf (2021))
dysgranular Bedini & Baldauf (2021)
several chemoarchitectonic features could segregate FEF from rostral regions in the middle frontal gyrus (MFG) and superior frontal gyrus. (Bedini & Baldauf (2021))

processing predominantly spatial information, mediating the set of overlapping functions of covert spatial attention, oculomotor control and spatial working memory. (Bedini & Baldauf (2021))
sensitivity to the stimulus context and sensory domain (Bedini & Baldauf (2021))
maintenance of goal-related information to control movement in a domain-specific way (Bedini & Baldauf (2021))
It is responsible for saccadic eye movements for the purpose of visual field perception and awareness, as well as for voluntary eye movement. (n.n)
The oculomotor system is informed about the evolving decision, not just the final outcome of the decision process. (n.n)
The accumulation of information revealed by FEF stimulation is only visible if the decision matches directly to known eye movements. (n.n)
involved in top-down attention and show evidence of sustained activity in response to a cue (Bedini & Baldauf (2021))

coactivations with medial oculomotor regions (the SCEF) and the SPL/IPL, bilateral ventral PFC, which included parts of the iFEF and the IFJ based on their localization relative to the iPCS and the IFS. (Bedini (2023) - Brain Structure) → siehe Ventrolateral PFC
reached by terminations of the SLF1 and SLF2 (Bedini & Baldauf (2021))
in the pathway of plPFC to posterior parietal and temporal cortices. (Bedini & Baldauf (2021))
core region of the DAN (Bedini & Baldauf (2021))
part of the cingulo-opercular network (Bedini & Baldauf (2021))

dysgranular BA6/8; ventral to sPCS–SFS; dorsal/where-stream
full topographic map of contralateral space
key functions: spatial attention, oculomotor control, spatial WM, top-down cue activity

Connectivity